Ambiguous Allele Combinations
Sequence Based Typing (SBT) as a method for defining the HLA type is well documented and most SBT typing strategies use the exon 2 and exon 3 sequences for HLA class I analysis and exon 2 for HLA class II analysis. Due to the heterozygous nature of SBT analysis, many pairs of alleles may give an ambiguous typing result. The documents here include a list of all alleles that are identical over exons 2+3 for HLA class I and all alleles that are identical over only exon 2 for HLA class II. This search tool provides an alternative method of viewing the ambiguous combinations currently detailed in the Microsoft XLSX file.
For more information regarding SBT Ambiguities please see our Ambiguity Documentation
Latest Ambiguity Files
For archived versions of the ambiguity PDF, XML or XLSX files please see our Ambiguity Archive