Multiple Sequence Alignment
The multiple alignment tool allows to display single locus alignments, as well as inter- and intra- species loci alignments from all groups within the IPD-MHC Database. This is achieved by a hybrid approach that combines precomputed alignments of single loci with dynamic inter- and intra- species sequence alignments. Where discrepancies have arisen between reported sequences and those stored in the database, the original authors have been contacted where possible, and necessary amendments to published sequences have been incorporated into this alignment. Future sequencing may identify errors in this list and the Nomenclature Committee would welcome any evidence that helps to maintain the accuracy of these sequence alignments.
Further help can be found in the help which details both the input options and how the alignments are displayed. Alignments can be downloaded from the download page.
HLA Genes
Help with Sequence Alignments
- Please select one or more loci by first choosing the species and then the gene. By clicking on the the locus name, the selection will be added below.
- The organism list can be filtered either by tags and/or by MHC group. The list of organism can be further filtered by writing into the input field in the Organisms section.
- An alternative reference sequence may be defined later by entering the allele name into the text box. The autocomplete form will aid the input selection.
- Where discrepancies have arisen between reported sequences and those stored in the database, the original authors have been contacted where possible, and necessary amendments to published sequences have been incorporated into this alignment. Future sequencing may identify errors in this list and the Nomenclature Committee would welcome any evidence that helps to maintain the accuracy of these sequence alignments.
Further more detailed help can be found in the help which details both the input options and how the alignments are displayed.