Equids
Welcome to the ELA Database, a specialist database for the Major Histocompatibility Complex genes of Equines. This page is intended as a resource for information on the nomenclature and DNA sequence data of the equine MHC complex. The data presented here is collected over published or submitted to public databases by many authors and has been manually curated by members of the MHC Nomenclature Committee of the International Society of Animal Genetics (ISAG).
Alleles
List all Equids alleles
Species
Species belonging to the Equids group
Align
Multi locus inter- and intra- species alignment
Nomenclature
Sequences have been officially named to adhere to approved MHC nomenclature (Ellis et al., 2006). Eqca refers to Equus Caballus, followed by the gene locus, and finally the major and minor types of alleles. Class I gene sequences can be found under the N locus in the Alignment Tool gene list.
Eqca-1
56
Class I
Eqca-2
45
Class I
Eqca-DQA1
19
Class II
Eqca-7
11
Class I
Eqca-DRB1
9
Class II
Eqca-N
7
Class I
Eqca-DQB1
7
Class II
Eqca-DRB2
7
Class II
Eqca-DMB
6
Class II
Eqca-16
6
Class I
Above are listed the most populated genes within the Equids group. To list all the genes within the ELA taxonomic group, please visit the species page.
Search ELA alleles
Group curator
Dr. Don Miller - dm96 [at] cornell.edu
Baker Institute for Animal Health, Immunology, United States
References
We hope you will cite the IPD-MHC database whenever you publish your sequences. When citing the database you can use the following articles.
Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, De Groot NG, Flicek P, Bontrop RE, Hammond JA and Marsh SGE IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Res. (2017), 45: D860–D864
Tseng CT, Miller D, Cassano J, Bailey E, Antczak DF Identification of equine major histocompatibility complex haplotypes using polymorphic microsatellites. Animal Genetics (2012), 41 (S2): 150-3