Suids
Welcome to the IPD-MHC Swine Leukocyte Antigen (SLA) website. The site is intended as a resource for information on the nomenclature and DNA sequence data for the genes of the swine MHC complex. The data presented represents work published or submitted to public databases by many authors and has been compiled and edited by the members of the SLA Nomenclature of the International Society for Animal Genetics (ISAG).
Alleles
List all Suids alleles
Species
Species belonging to the Suids group
Align
Multi locus inter- and intra- species alignment
Nomenclature
Strict quality standards for DNA sequencing are essential to prevent naming of large numbers of non-existent alleles. For this reason a nomenclature guideline for acceptance of new sequences for allele name assignment is available.
SLA-2
105
Class I
SLA-1
100
Class I
SLA-DRB1
99
Class II
SLA-DQB1
55
Class II
SLA-3
47
Class I
SLA-DQA
27
Class II
SLA-DRA
16
Class II
SLA-DRB2
12
Class II
SLA-6
10
Class I
SLA-DMA
7
Class II
Above are listed the most populated genes within the Suids group. To list all the genes within the SLA taxonomic group, please visit the species page.
Search SLA alleles
Group curator
Dr. Sam Ho - sho [at] giftofhope.org
Gift of Hope Organ & Tissue Donor Network, Histocompatibility and Infectious Disease Testing Laboratory, United States
References
- Smith DM, Lunney JK, Martens GW, Ando A, Lee JH, Ho CS, Schook L, Renard C, Chardon P Nomenclature for factors of the SLA class-I system, 2004 Tissue Antigens (2005), 65:136-9
- Smith DM, Lunney JK, Ho CS, Martens GW, Ando A, Lee JH, Schook L, Renard C, Chardon P Nomenclature for factors of the swine leukocyte antigen class-II system, 2005 Tissue Antigens (2005), 66:623-9
- Ho CS, Lunney JK, Ando A, Rogel-Gaillard C, Lee JH, Schook LB, Smith DM Nomenclature for factors of the SLA system, update 2008 Tissue Antigens (2009), 73:307-15
- Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, De Groot NG, Flicek P, Bontrop RE, Hammond JA and Marsh SGE IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Res. (2017), 45: D860–D864