Suids

Welcome to the IPD-MHC Swine Leukocyte Antigen (SLA) website. The site is intended as a resource for information on the nomenclature and DNA sequence data for the genes of the swine MHC complex. The data presented represents work published or submitted to public databases by many authors and has been compiled and edited by the members of the SLA Nomenclature of the International Society for Animal Genetics (ISAG).

Nomenclature

Strict quality standards for DNA sequencing are essential to prevent naming of large numbers of non-existent alleles. For this reason a nomenclature guideline for acceptance of new sequences for allele name assignment is available.

SLA-2

105

Class I

SLA-1

100

Class I

SLA-DRB1

99

Class II

SLA-DQB1

55

Class II

SLA-3

47

Class I

SLA-DQA

27

Class II

SLA-DRA

16

Class II

SLA-DRB2

12

Class II

SLA-6

10

Class I

SLA-DMA

7

Class II

Above are listed the most populated genes within the Suids group. To list all the genes within the SLA taxonomic group, please visit the species page.

Search SLA alleles

Group curator

Dr. Sam Ho - sho [at] giftofhope.org

Gift of Hope Organ & Tissue Donor Network, Histocompatibility and Infectious Disease Testing Laboratory, United States

References

  • Smith DM, Lunney JK, Martens GW, Ando A, Lee JH, Ho CS, Schook L, Renard C, Chardon P Nomenclature for factors of the SLA class-I system, 2004 Tissue Antigens (2005), 65:136-9
  • Smith DM, Lunney JK, Ho CS, Martens GW, Ando A, Lee JH, Schook L, Renard C, Chardon P Nomenclature for factors of the swine leukocyte antigen class-II system, 2005 Tissue Antigens (2005), 66:623-9
  • Ho CS, Lunney JK, Ando A, Rogel-Gaillard C, Lee JH, Schook LB, Smith DM Nomenclature for factors of the SLA system, update 2008 Tissue Antigens (2009), 73:307-15
  • Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, De Groot NG, Flicek P, Bontrop RE, Hammond JA and Marsh SGE IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Res. (2017), 45: D860–D864